Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center

Pediatric Ewing’s Sarcoma: Unusual Presentations

Authors

  • Ruqayya Manzoor Assistant Professor, Department of Pediatric Oncology, Children Hospital Pakistan Institute of Medical Sciences, Islamabad, Pakistan
  • Nuzhat Yasmeen Professor and HOD, Department of Pediatric Oncology, Children Hospital, Pakistan Institute of Medical Sciences, Islamabad, Pakistan
  • Hijab Shaheen Senior Medical Officer, Department of Pediatric Oncology, Children Hospital Pakistan Institute of Medical Sciences, Islamabad, Pakistan
  • Junaid Jamshed Clinical Research Coordinator, Pakistan Society of Pediatric Oncology, Islamabad, Pakistan.

DOI:

https://doi.org/10.51846/jucmd.v4i2.4025

Keywords:

Ewing's Sarcoma, Paediatric Bone Tumor, Intracranial Extension, Metastasis, Histopathology, Immunohistochemistry

Abstract

We present a case series of three pediatric patients diagnosed with Ewing’s sarcoma at distinct anatomical sites—the scalp with intracranial extension, the forearm involving bone, and the lumbar region with metastatic spread. Each patient underwent a detailed clinical assessment, radiological imaging, histopathology, and immunohistochemistry for diagnosis. Treatment comprised a multidisciplinary approach including surgical resection, chemotherapy, and radiotherapy. Our findings highlight the diverse clinical manifestations, diagnostic challenges, and the critical role of early detection and individualized treatment strategies in optimizing outcomes for Ewing’s sarcoma patients.

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Published

16-06-2025

How to Cite

1.
Manzoor R, Nuzhat Yasmeen, Hijab Shaheen, Junaid Jamshed. Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center: Pediatric Ewing’s Sarcoma: Unusual Presentations. J Univ Coll Med Dent. [Internet]. 2025 Jun. 16 [cited 2026 Mar. 29];4(2):189-92. Available from: https://testjournals.uol.edu.pk/index.php/jucmd/article/view/4025

Issue

Volume 4 Issue 2

Section

Case Report / Case Series

License

Copyright (c) 2025 Dr. Ruqayya Manzoor

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